PHARMACOGENETIC (PGx) TESTING
THE MOST ADVANCED MOLECULAR METHODOLOGY FOR MEDICATION MANAGEMENT
Pharmacogenetics is the study of genetic factors determining variability in response to drugs in terms of both efficacy and toxicity. While many medications have PGx information available, without insight into patients’ genetics, clinicians must rely on trial-and-error methods when prescribing medications.
Navis tests for 60 genes and provides medication guidance on 18 drug classes with one painless cheek swab. The results can provide guidance for new prescriptions and future FDA-approved medications.
The end result is a patient-centered, value-based care solution that enables providers to make informed treatment decisions and helps to avoid inappropriate therapies, excess costs, adverse drug events and the progression of disease.
WHY PHARMACOGENETIC TESTING?
Integrating PGx testing into a treatment plan can help decrease the risk of adverse drug reactions (ADRs), reduce trial and error prescribing and pharmacotherapy failure rates, and improve drug dose optimization. The personal and interactive nature of PGx-informed care helps to address key factors such as perceived need or efficacy, cost, and concerns about side effects, that lead to poor medication adherence.
1.5 million people visit emergency departments for ADRs each year, and almost 500,000 require hospitalization.
Drug prescriptions guided by PGx testing can potentially reduce clinically relevant ADRs by 30%.
Nonadherence to prescribed medications is estimated to cause 125,000 preventable deaths per year.
PGx information about gene-drug interactions is included in the drug labeling of more than 400 FDA-approved medications.
The ideal time to conduct pharmacogenetic testing is prior to the administration of relevant medications so that the right drug at the optimal dose can be given.
— https://doi.org/10.3389/fmed.2023.1006743
MINIMIZES ADVERSE DRUG REACTIONS
Reduces potential adverse drug reactions and drug-to-drug interactions, ED visits and 30-day hospital readmissions.
IMPROVES PATIENT CARE AND OUTCOMES
Increases patient engagement in treatment decisions and addresses concerns that may lead to poor medication adherence.
DECREASES HEALTH CARE COSTS
Diminishes trial and error methodology and maximizes drug dose response for more effective medical care.
SIMPLE, PAINLESS TEST
Non-invasive, painless collection using a cheek swab application that can be done at the physician’s office or by the patient in their own home.
Navis Clinical Laboratories offers several testing options to enhance disease diagnosis, treatment selection and monitoring, and improve health care decision-making and patient outcomes. Contact us today to learn more about our toxicology, molecular and clinical testing options.