PHARMACOGENETIC (PGx) TESTING
THE MOST ADVANCED MOLECULAR METHODOLOGY FOR PRECISION MEDICINE
Pharmacogenetics is the study of genetic factors determining variability in response to drugs in terms of both efficacy and toxicity. While many medications have PGx information available, without insight into patients’ genetics, clinicians must rely on trial-and-error methods when prescribing medications.
Navis tests for variants in relevant genes and provides medication guidance on 18 drug classes applicable to current and new prescriptions.
The end result is a patient-centered, value-based care solution that enables providers to make informed treatment decisions and helps to avoid inappropriate therapies, excess costs, adverse drug events and the progression of disease.
90% of the general population likely carries at least one actionable PGx variant in one of five well-established drug-gene interactions, suggesting preemptive PGx genotyping may benefit most individuals, with particular value in individuals taking multiple medications.
WHY PHARMACOGENETIC TESTING?
Optimizing drug therapy with PGx intervention can help guide provider selection of effective drugs and/or dosages, and reduce ED visits and hospitalizations associated with serious ADRs. Additionally, the personal and interactive nature of PGx-informed care can help improve medication adherence by addressing patient concerns about perceived need or efficacy, cost and side effects.
1.5 million people visit emergency departments for ADRs each year, and almost 500,000 require hospitalization.
Drug prescriptions guided by PGx testing can potentially reduce clinically relevant ADRs by 30%.
Nonadherence to prescribed medications is estimated to cause 125,000 preventable deaths per year.
PGx information about gene-drug interactions is included in the drug labeling of more than 400 FDA-approved medications.
MINIMIZES ADVERSE DRUG REACTIONS
Drug prescriptions guided by PGx testing can potentially reduce clinically relevant ADRs by 30%.
IMPROVES ADHERENCE AND OUTCOMES
Engaging patients in PGx-informed medication decisions may improve patient knowledge and trust, resulting in improved medication adherence.
DECREASES HEALTH CARE COSTS
PGx-informed decisions may result in reduced patient costs associated with trial and error of prescription medications for treatment
SIMPLE, PAINLESS TEST
Noninvasive, painless cheek swab collection performed in the provider’s office.
LIFELONG BENEFIT FOR PATIENT
Because DNA information does not change, patients can share their test results with other prescribers throughout their lifetime.
Make prescribing safer. Make treatment faster. Make care more personal.
Navis Clinical Laboratories. Bringing precision medicine to the heart of behavioral health care.