Ecstasy (MDMA, MDEA and MDA)

Classification: Entactogenic, of the phenethylamine and amphetamine families; hallucinogen

Background: Ecstasy is a group of drugs typically consisting of MDMA, MDEA and MDA that are all psychotropic derivatives of the amphetamines drug class. MDMA is a ring-substituted derivative of methamphetamine first synthesized in 1914 and later evaluated as an adjunct to psychotherapy in the 1970s. MDA is a minor metabolite of MDMA, which can also be abused separately, first synthesized in 1910. MDEA is a close chemical analog of MDMA  and is a methoxylated amphetamine derivative. In 1985 the widespread abuse of these drugs caused the U.S. Drug Enforcement Administration to classify the compounds as Schedule I drugs. There is no current prescribed use for these drugs.

Street Names: E, X, Thizz, Ecstasy, Adam, XTC, STP, Eve, Molly

Appearance: Tablet form available in multiple colors and shapes

Mode(s) of Use: Oral consumption in pill form

Physiological Effects: Increased energy, endurance, alertness, awareness, desire, drive, motivation, analgesia and decreased pain sensitivity, jaw clenching and grinding of the teeth. Coming down from the drug causes: loss of appetite, vertigo, GI disturbances, insomnia, aches and pains, exhaustion, and jaw soreness from jaw clenching.

Psychological Effects: Euphoria, increased sexual arousal, sense of intimacy, diminished anxiety, depression, aggression, hostility and jealousy, alteration of consciousness, feelings of empathy and compassion for others, improved self-confidence.

Withdrawal Effects: Anxiety, paranoia, fatigue, depression, irritability and impaired attention and focus.

Toxicity: Confusion, panic attacks, hypomania, hallucinations, memory impairment, disorganized thinking, delirium/insanity, muscle twitching, hyperreflexia, rapid breathing, heart palpitations, chest pains, cardiac arrhythmias, circulatory shock, destruction of blood vessels, cardiac arrest, hemorrhage/stroke, hyperthermia, organ failure, brain damage, coma and death.

Metabolism: MDMA excretes in urine as MDMA and MDA. MDEA is largely eliminated as the parent drug. MDA is also largely eliminated as an unchanged parent drug.

Detection Time in Urine: 1–3 days 

Detection Time in Oral Fluid: 1–2 days

chemical structure of mdma ecstacy

Questions? Contact us!

The information provided is for educational purposes only and is not intended to be used as medical or legal advice. Detection times are approximate and may be influenced by a number of factors, including BMI, duration of drug use, dosage and interindividual metabolic differences. For specific drug testing result interpretation questions, please contact us.


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